Hi Jeremy 

thanks for your response. below is the config I have am using it for mail relay. No i didnt use the Confconsole because I didnt know of it. 

# See /usr/share/postfix/main.cf.dist for a commented, more complete version

# Debian specific:  Specifying a file name will cause the first
# line of that file to be used as the name.  The Debian default
# is /etc/mailname.
#myorigin = /etc/mailname

smtpd_banner = $myhostname ESMTP
biff = no

# appending .domain is the MUA's job.
append_dot_mydomain = no

# Uncomment the next line to generate "delayed mail" warnings
#delay_warning_time = 4h

readme_directory = no

# See http://www.postfix.org/COMPATIBILITY_README.html -- default to 2 on
# fresh installs.
compatibility_level = 2

# TLS parameters
smtpd_tls_cert_file=/etc/ssl/certs/ssl-cert-snakeoil.pem
smtpd_tls_key_file=/etc/ssl/private/ssl-cert-snakeoil.key
smtpd_use_tls=yes
smtpd_tls_session_cache_database = btree:${data_directory}/smtpd_scache
smtp_tls_session_cache_database = btree:${data_directory}/smtp_scache

# See /usr/share/doc/postfix/TLS_README.gz in the postfix-doc package for
# information on enabling SSL in the smtp client.

smtpd_relay_restrictions = permit_mynetworks permit_sasl_authenticated defer_unauth_destination
myhostname = mydomain.com
mydomain = mydomain.com
alias_maps = hash:/etc/aliases
alias_database = hash:/etc/aliases
myorigin = $mydomain
mydestination = $myhostname, localhost.localdomain, localhost
mynetworks = 127.0.0.0/8 [::ffff:127.0.0.0]/104 [::1]/128
relayhost = [smtp.office365.com]587
mailbox_size_limit = 0
recipient_delimiter = +
inet_protocols = ipv4
smtp_sasl_auth_enable = yes
smtp_sasl_password_maps = hash:/etc/postfix/sasl_passwd
smtp_sasl_security_options = noanonymous
smtp_tls_security_level = may
header_size_limit = 4096000
sender_canonical_maps = regexp:/etc/postfix/sender_canonical
smtp_tls_CAfile = /etc/postfix/cacert.pem
smtp_use_tls = yes
smtp_generic_maps = hash:/etc/postfix/generic

#myorigin = /etc/mailname
mynetworks_style = subnet